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Simian Flu

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ALZ-112 and ALZ-113

Canisters of the ALZ-112 and ALZ-113.

The Simian Flu, formerly known as ALZ-112 and ALZ-113, was an artificially created retrovirus designed to cure Alzheimer's disease. The brainchild of Dr. Will Rodman of the Gen-Sys Laboratories, the first virus proved a success with ape test subjects by greatly enhancing their intelligence, and managed to temporarily cure Rodman's own father. In order to make the effects permanent in humans, a second, more powerful and contagious strain was created which ultimately proved fatal to humans, leading to their ultimate global downfall and the rise of the Evolved Apes.





ALZ-112 was the codename of a viral "cure" for Alzheimer's Disease developed over the course of five-and-a-half years by geneticist Dr. Will Rodman at the Gen-Sys Laboratories. Among the chimp test subjects were Bright Eyes, Lorelei, Chambers, Burke and Verdon. A military-sanctioned "variant" of the drug was administered to Burke and Verdon, the latter of whom was later shot attempting to escape.[1] Bright Eyes displayed the desired results, and was to be exhibited during a board meeting, but was killed by security guards after she became aggressive in defence of her newborn infant, Caesar (CE). Funding for the project was cut as a result, but Rodman adopted Caesar, who inherited his mother's increased intelligence. Rodman secretly stole samples of the 112 virus to administer to his father Charles, who was himself an Alzheimer's sufferer. Although Charles' condition initially improved, his body gradually developed antibodies against the virus, and he regressed to his former condition five years later. Desperate to create a stronger strain, Will reported his unauthorized experiments to Gen-Sys head Steven Jacobs, who was impressed enough by Will's testimony to authorize the creation of the "ALZ-113".[2]

Bright Eyes' Eye

One of the side effects of the ALZ-112.



During the first trial, the virus was accidentally released onto chimp handler Robert Franklin after the test ape, Koba, briefly broke out of his restraints and breached one of the viral containers. Although Koba displayed the same increased intelligence possessed by apes subjected to the previous 112 variant, the new virus proved fatal to Franklin. Rodman became aware of Franklin's death, and attempted to halt the tests, but was rebuffed by Jacobs. Unknown to Rodman, Franklin had accidentally sneezed on airline pilot Douglas Hunsiker before dying, thus begining a wave of infections which would later result in a global pandemic. Caesar, who in the meantime had been detained in the San Bruno Primate Shelter, managed to escape his captivity and steal several cannisters containing the virus, which he used to increase the intelligence of his cell-mates. He and his followers later escaped the Shelter, precipitating the Monkeygate scandal.[2]


New WorldEdit

A day after the Monkeygate scandal occurred, the confirmed deaths of eight people from the virus in the San Francisco area prompted the CDC and the WHO to declare a medical emergency and implement quarantine procedures. Less than a week later, the nationwide death toll had reached over 250,000. With no sign of a cure, San Francisco went into chaos, with citizens looting pharmacies and overwhelming hospitals. The breakdown of law and order resulted in the intervention of the National Guard, and the appearance of various domestic terrorist groups, including Alpha/Omega and separatists in southern California. In Tenessee, Muslims were used as scapegoats, and many were beaten to death. Once the connection between the virus and the escaped evolved apes became public knowledge, rioting mobs broke into various zoos and began killing apes, monkeys, and all other superficially simian-like mammals like tarsiers and sloths.[3]

Old WorldEdit

As in San Francisco, numerous major cities in Eurasia, including London, Paris, Rome and Shanghai saw widespread rioting and looting. In Belarus, an understaffed nuclear power plant went into meltdown. In the former Yugoslavia, fighting broke out between Serbs and Croats, with similar conflicts being reported among Hutus and Tutsis in Africa and Sunnis and Shi'ites in the Muslim world. In eastern China, the government went on a brutal crackdown of rebelling ethnic minorities. In the Democratic Republic of Congo, fighting broke out between North and South Kivu, dividing the region on ethnic and tribal grounds. Indonesia saw fewer cases of infection, and closed its borders. In Egypt, Muslims began burning Christians alive, and in India, a chemical spill in the Ganges resulted in some people seeing the burning river as a religious sign, and began immolating themselves in its waters.[3]



Douglas Hunsiker's nose bleeding - a symptom of ALZ-113 in humans.

The virus greatly increases the intelligence of non-human primates, and can be inherited by the young of infected apes. The only physically notable symptom is the adoption of a green tint in the infected apes' irises.[2] In contrast, the virus is lethal to humans. Both Malakai Youmans and Natalia Kosar noted similarities between the way Simian Flu affected humans and Ebola, as both are highly contagious and have hemorrhagic fever as a primary symptom.[3]


  • 112 was the running time, in minutes, of the original Planet of the Apes movie.
  • Two earlier versions of the script used the name "RT 112", which the producers felt was ludicrous, and "ADV 112" - shorthand for "adenovirus".
  • There is a set photo from the set of Dawn of the Planet of the Apes of a wall with the caption "ALZ-113" in reference of this "cure".



  1. Rise of the Planet of the Apes (webcomic)
  2. 2.0 2.1 2.2 Rise of the Planet of the Apes
  3. 3.0 3.1 3.2 Dawn of the Planet of the Apes: Firestorm - The Official Movie Prequel

External LinkEdit

The Simian Flu and You

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